Endocrine Abstracts

Introduction: Medical specialization model in Spain is carried out through specialized health training, through the residency program. Residents are a key element for the proper functioning of today’s National Health System. The aim of the study is to analyze, by an anonymous survey, the opinion of three aspects among final-year residents in Endocrinology and Nutrition (E&N): self-assessment of the knowledge acquired, working prospects, care and training consequences ...

Introduction: Familial Adenomatous Polyposis (FAP) is an autosomal dominant disease classically characterized by the development of hundreds or thousands of adenomas in the rectum and colon during the second decade of life. Almost all patients will develop colorectal cancer (CRC) if not identified and treated at an early stage. It is a multisystem growth disorder so there is an increased risk of developing extraintestinal manifestations. In this context, an increase in adrenal...

Introduction: Cancer is the result of genetic and epigenetic alterations generating uncontrolled cell growth. These molecular changes maintain an immunosuppressive microenvironment allowing tumor spread. Immune checkpoint inhibitors (ICI) are novel therapeutic strategies in cancer treatment, promoting anti-tumor response by boosting cytotoxic T lymphocytes. Despite their high effectiveness, they can trigger the activation of diverse autoimmune diseases in genetically predispos...

Introduction: Familial Adenomatous Polyposis (FAP) syndrome is an autosomal dominant disorder associated with a high risk of multiple intestinal and extraintestinal cancers. They develop hundreds or thousands of adenomas in the rectum and colon during the second decade of life that. If they are not identified and treated, almost all patients develop colorectal cancer (CRC) and die by the age of 40-50 years. Thyroid carcinoma is a FAP manifestation with an unknown reported high...

Bariatric surgery (BS) improves quality of life and health due to the beneficial effect on the metabolism at multiple levels. Specifically, its effectiveness in weight loss and the attenuation or resolution of comorbidities associated with obesity, means lower morbidity and mortality compared to other types of interventions. The objective is to analyze the evolution of obesity-related diseases after twelve months of follow-up.Methods: Retrospective study...

Introduction: Diabetic retinopathy (DR) is the most common microvascular complication in patients with type 1 diabetes (T1D), and the role of lipids in the development of this complication is still controversial. In this study we have analyzed the association between lipid levels at onset and during the follow-up and the subsequent development of DR.Methods: The cohort consists of 1132 patients with T1D who were diagnosed in Navarra between 1/1/1990 and ...

Introduction: Lingual thyroid ectopia is a rare congenital abnormality affecting embryogenesis of the gland descent from foregut through pre-tracheal region in the neck. Most cases have an asymptomatic course but may occasionally produce local obstructive symptoms. Diagnostic methods are 99mTc, 131I or 123I radionuclide scan, computed tomography scan, magnetic resonance, and ultrasound. Surgery is the elective treatment for cases presenting com...

Introduction: An increased risk of thyroid disease (TD) has been described in patients with type 1 diabetes (DM1) with respect to the general population. The objective is to establish the incidence and characterize the differences in patients who develop TD in relation to the debut of DM1 (previous, concurrent or a posteriori).Materials and methods: Retrospective study of 1126 patients followed up in Endocrinology consultations in Navarra. Three types of...

Objective: To understand the factors associated with changes in thyroid nodule volume with previous benign citology.Material and Methods: This is a prospective single-center observational study. We included patients with a benign citology from March/2016 to May/2018 and ultrasound follow-up after 12–24 months. Initially we determined the nodule size (volume in ml), and its risk of malignancy was classified according to ATA 2015 criteria. Volume cha...